Hi immortal nieces,

I'm collecting 14 million data points on my body across my menstrual cycle... 100 tasks a day, over 50 devices, a 12-person medical team.

Bryan mapped his baseline in a couple of weeks. Mine will take ~100 days… because the female body isn't static. It changes across the cycle. Total cholesterol alone can swing ~19% in a single cycle. Glucose, temperature, sleep, skin, mood… all of it moves with hormones. We're measuring everything… hormones, brain, skin, gut, blood, sleep, vaginal microbiome, core temperature, etc.

I also have endometriosis. So do 1 in 10 women. It takes years to diagnose and has no cure… we’re going to try and resolve my endo non-invasively.

Female health is severely understudied. Right now, the lived female experience gets dismissed… but data and numbers are hard to dismiss.

I'll share everything with you for free. Good, bad, what works, what fails.

👇 Results and updates

(this is a newsletter - you can unsubscribe any time - you will receive emails from me, bryan johnson, and Immortals)

—————

My most common questions:

HORMONES: how I test my hormones daily →
ENDOMETRIOSIS: how to get tested → (coming soon)
VAGINAL MICROBIOME: how to test → (coming soon)
RESULTS: where I am publishing →
SKIN: my skin protocol →
HAIR: my hair protocol → (coming soon)
FOOD: what I eat → (coming soon)
PROTOCOL: what I do daily → (coming soon)
BUSINESS: the business I co-founded →
PRESS/CONTACT: how to contact me →

Pleaaaaaaseee don’t feel pressure to do anything I do… I am trying to do this unhinged precisely so you don’t have to. <3 Also.. none of this is medical advice, and always talk to your doctor. Also.. my protocol evolves.. So it's highly likely this document is out of date (bear with me).

—————

RESULTS

I am still figuring out the best system to share results… for now, the best place to follow along is socials:

Instagram → here
TikTok → here
X → here

Email:

(this is a newsletter - you can unsubscribe any time - you will receive emails from me, bryan johnson, and Immortals)

—————

SKIN PROTOCOL

Over the past few years, despite being age 30, I’ve reversed my skin age to 21.

This is based on a scanning device that measures 8 skin markers using multispectral imaging.

I took a scientific approach to reverse my skin age… and you can too. This is a long write up... I am going to share every treatment and intervention I’ve done for my skin.

how skin measurement works
my skin protocol
how to start
how to track

Before I dive in, it’s important to note that facial aging is made up of many different parts.

Aging affects…

bone structure
collagen
hydration
elasticity
fat
placement of tissue (gravity)

This post focuses on specific key facial aging markers, and it does not cover them all. So, I am not saying I look 21 years old… or that I am 21 years old according to all skin markers. Just the specific key skin markers that multi-spectral imaging can measure.

And according to those 8 markers, my skin age is 21 years old.

It’s also worth noting that 5 years ago, I was eating McDonald's daily and did not do anything specific for my skin…

Then I met Bryan Johnson. We started our scientific health experiment together, and I started to change my core habits, which no doubt had a major impact on my overall aging.

Here’s the earliest face scan I can find.

at age 27, my skin was age 26.
now age 30, my skin is age 21. (based on multispectral imaging measuring 8 skin markers)

This means that in 3 years, instead of accumulating 3 years of skin age, I reversed my skin age by 5 years.

How does skin measurement work?

This device uses multispectral imaging. It uses standardized visible, polarized, and UV lighting to assess surface and subsurface skin features. It is a well-validated skin-analysis tool.

This measurement does a lot, but not everything.

What it DOES measure:

spots
pores
wrinkles
texture
UV spots
brown spots
red areas
porphyrins (bacterial byproducts, which highlight congestion)

It does NOT measure:

collagen
elasticity of skin
structural bone
plenty else

Currently, there’s no easy way to measure things like collagen and bone loss.

My skin protocol

Below is everything I’ve done for my skin, both present and past:

hyaluronic acid supplement
vitamin C supplement
copper supplement
vitamin D supplement
other supplements listed below
microdose of Accutane
avoid sun UV rays
better sleep
better nutrition
better exercise
BHA (beta hydroxy acid)
niacinamide
azelaic acid
tretinoin
red light therapy
microneedling
IPL (BBL)
Sculptra
1550-nm laser
Sofwave
595-nm pulsed dye laser

I also use the products below for skin health. They’re an important part of my protocol, so it would be weird not to mention them… but they’re also from our business. You can get these things from us or somewhere else. I don’t mind.

Blueprint supplements and foods:

Blueprint skincare:

Some important notes….

1) All of these products are just one part of a larger health routine… so none of these products alone have reduced my skin age.

2) I achieved these results without Botox and filler. You can too. Since getting these results, I’ve dabbled with Botox and filler for facial balancing, which is a whole other art form. I’ll share more about those results soon.

How do you start?

Do these 5 things:

Treat any major conditions
Add basic interventions
Get a face scan
Target specific problems
Retest

Here’s a breakdown of each step…

#1 Treat diseases and conditions

If you have something major going on, this is the most important step to start with. I use the word “disease” intentionally because people think skin = vanity. But these are medical conditions…. and diseases and medical conditions should be diagnosed and treated by a medical provider.

Examples:

acne
rosacea
eczema
psoriasis
actinic keratosis
seborrheic dermatitis
melasma

In my case, I had been struggling with acne for years. It was a horrible experience, but I didn’t take it seriously.

I started microdosing Accutane and my life changed. (I do 40 mg a week under physician supervision.)

Each major condition has a different treatment plan. Chat with an LLM and your doctor, and follow a science-backed treatment path (not random marketing gimmicks).

#2 Basic interventions

Some general things I’d recommend for almost everyone:

avoid UV damage
red light therapy
moisturize and cleanse
better sleep
better nutrition
exercise

And slightly more advanced:

collagen peptides (also good for joints)
hyaluronic acid supplement
vitamin C supplement
tretinoin
extra virgin olive oil daily
skin-bioavailable carotenoid antioxidants (astaxanthin, lutein, and zeaxanthin)

#3 Get a face scan

These aren’t consumer devices, but plenty of clinics have them. Search online for “VISIA” to find somewhere local. Important: take a photo of your results for your records.

Each result will include a percentile. The higher the number, the better.

For example: “red areas 55%”

This means you are in the 55th percentile for your age group and skin type. Said another way, you are better than 55% of other people in this marker. This would also mean you’re around average, or expected, for your age.

#4 Target specific problems

Now you know where your skin is thriving and where it is struggling.

Here is an example scorecard:

98% red areas (good)
90% porphyrins (good)
88% pores (good)
76% texture (good)
28% brown spots (bad)
19% wrinkles (bad)
12% UV spots (bad)

Next, ask your favorite LLM and doctor about scientifically backed treatments for that specific problem. Be clear that you want treatments that are clinically proven. Put together a treatment plan.

Example treatments:

wrinkles = tretinoin
UV damage = protect from sun
brown spots = hydroquinone

It’s important that for each treatment you check what the potential risks are and make sure you’re informed by your doctor (ideally a dermatologist).

In almost all cases, protecting your skin from sun damage is a 10/10 treatment option.

Do this:

sunscreen
cover your skin when outside (hat, umbrella, face cloth, etc.)
tint your car windows

#5 Retest

Once you’ve tried a treatment, go back and rescan your face. Repeat this process, and watch your numbers change.

Skin is just like any other biological organ. You can:

measure
diagnose
treat
repeat

It annoys me that most of the skincare advice on social media is filled with useless noise.

For women, this is especially important, because obviously beauty is a commodity that is sold to women, and most of the time the things they’re selling don’t work.

Knowing how to measure your skin is your best protection against this, for everyone.

Skin is cool and important, but we’re about to spend millions to measure and decode my biology through every phase of the menstrual cycle. Optimizing health for a female means understanding female biology first… the cycle, hormonal transitions, things that have never been properly measured.

In the end, what I want is for women to have agency over their own aging: to be understood, and to make real choices about their bodies with real evidence behind them.

—————